Comparison of Optic Disc Morphology of Optic Nerve Atrophy between Compressive Optic Neuropathy and Glaucomatous Optic Neuropathy

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Comparison of Optic Disc Morphology of Optic Nerve Atrophy between Compressive Optic Neuropathy and Glaucomatous Optic Neuropathy

OBJECTIVES To compare the optic nerve head (ONH) structure between compressive optic neuropathy (CON) and glaucomatous optic neuropathy (GON), and to determine whether selected ONH quantitative parameters effectively discriminate between GON and CON, especially CON cases presenting with a glaucoma-like disc. METHODS We prospectively assessed 34 patients with CON, 34 age-matched patients with ...

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Evaluation of inducible nitric oxide synthase in glaucomatous optic neuropathy and pressure-induced optic nerve damage.

PURPOSE To determine whether inducible nitric oxide synthase (NOS-2) is involved in glaucomatous optic neuropathy. METHODS Chronic elevation of rat intraocular pressure (IOP) leading to optic nerve damage was induced by episcleral injection of hypertonic saline, which caused sclerosis and blockade of aqueous humor outflow pathways. Expression of NOS-2 in the retina and optic nerve head (ONH) ...

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Glaucomatocyclitic crisis and glaucomatous optic neuropathy

Glaucomatocyclitic crisis is a rare disease first described by Posner and Schlossman1 in 1948. The disease is characterized by unilateral recurrent attacks of increased intraocular pressure (IIOP) associated withmild anterior uveitis and an open angle.1,2 It is classified as an inflammatoryglaucoma. In contrast to the commonpresentations of eye pain andnausea in acute angle-closure glaucoma, th...

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Anterior ischemic optic neuropathy in eyes with optic disc drusen.

BACKGROUND There have been anecdotal reports of anterior ischemic optic neuropathy (AION) occurring in eyes with optic disc drusen (ODD), but the clinical features of this condition have not been well characterized. OBJECTIVES To better describe the clinical features of AION associated with ODD and to compare the clinical features of this condition with those of "garden variety" nonarteritic ...

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Pathophysiology of Glaucomatous Optic Neuropathy: Role of Optic Nerve Head Vascular Insufficiency

In 1970, based on my experimental and clinical studies, I defined glaucoma as: “a disease wherein the normal balance between the intraocular pressure and the blood pressure in the choroidal vessels supplying the optic disc and retrolaminar part of the optic nerve is disturbed, resulting in vascular insufficiency in the optic disc and retrolaminar part of the optic nerve, and hence in visual fie...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2014

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0112403